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broccoli sprout extracts (bse)  (Johns Hopkins HealthCare)

 
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    Johns Hopkins HealthCare broccoli sprout extracts (bse)
    Mean bioavailability of sulforaphane from <t> broccoli </t> sprout and seed preparations rich in glucoraphanin, as affected by matrix, mode, of delivery, and activity of myrosinase on its substrate.
    Broccoli Sprout Extracts (Bse), supplied by Johns Hopkins HealthCare, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/broccoli sprout extracts (bse)/product/Johns Hopkins HealthCare
    Average 90 stars, based on 1 article reviews
    broccoli sprout extracts (bse) - by Bioz Stars, 2026-02
    90/100 stars

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    1) Product Images from "Sulforaphane Bioavailability from Glucoraphanin-Rich Broccoli: Control by Active Endogenous Myrosinase"

    Article Title: Sulforaphane Bioavailability from Glucoraphanin-Rich Broccoli: Control by Active Endogenous Myrosinase

    Journal: PLoS ONE

    doi: 10.1371/journal.pone.0140963

    Mean bioavailability of sulforaphane from broccoli sprout and seed preparations rich in glucoraphanin, as affected by matrix, mode, of delivery, and activity of myrosinase on its substrate.
    Figure Legend Snippet: Mean bioavailability of sulforaphane from broccoli sprout and seed preparations rich in glucoraphanin, as affected by matrix, mode, of delivery, and activity of myrosinase on its substrate.

    Techniques Used: Activity Assay

    Preparations are: Commercial broccoli seed extract (BSdE) formulated into gel-caps at 69 and 230 μmol/dose (10.4% conversion overall; , Cohort 3), and JHU BSE formulated (by Xymogen) into molar equivalent doses (10.3% conversion overall; , Cohort 2). There is no difference among the treatment groups overall (p = 0.0651 by repeated measures anova)
    Figure Legend Snippet: Preparations are: Commercial broccoli seed extract (BSdE) formulated into gel-caps at 69 and 230 μmol/dose (10.4% conversion overall; , Cohort 3), and JHU BSE formulated (by Xymogen) into molar equivalent doses (10.3% conversion overall; , Cohort 2). There is no difference among the treatment groups overall (p = 0.0651 by repeated measures anova)

    Techniques Used:



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    Preparations are: SF-, GR-, or GR plus Myrosinase-rich; they are delivered either in water, juice, or gel-caps; and they are derived from either sprouts or seeds, as indicated at top of graph. Boxes around data points delineate the 25 th to 75 th percentile of values, and whiskers delineate the 5 th and 95 th percentiles. Solid line through middle of box is the mean. “Cohort numbers” in the following are from : (A) Hospitalized subjects given SF-rich <t>BSE</t> (mean 68.9%, data from Ref. ); (B) Hospitalized subjects given GR-rich BSE (mean 18.0%, data from Ref. ); (C) Free-living subjects given GR-rich BSE (mean 11.8%, data from Ref. ); (D) Cohort 1 (BSE in water; mean 9.4%); (E) Cohort 3 (Xymogen BSdE in gel-caps; mean 10.4%); (F) Cohort <t>2</t> <t>(JHU</t> BSE in gel-caps; mean 10.3%); (G) Cohort 6 (FDBS in dilute pineapple-lime juice; mean 44%); (H) Cohort 5 (FDBS in acid-resistant gel-caps; mean 32.7%); ( I) Cohort 5 (FDBS in regular gel-caps; mean 35.1%); (J) Cohort 4 (BSdP; 35.9%). There is a highly significant difference between the means of D through F a (10.3%), and G through J b (39.6%), (p = 0.0000, by oneway anova).
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    Preparations are: SF-, GR-, or GR plus Myrosinase-rich; they are delivered either in water, juice, or gel-caps; and they are derived from either sprouts or seeds, as indicated at top of graph. Boxes around data points delineate the 25 th to 75 th percentile of values, and whiskers delineate the 5 th and 95 th percentiles. Solid line through middle of box is the mean. “Cohort numbers” in the following are from : (A) Hospitalized subjects given SF-rich <t>BSE</t> (mean 68.9%, data from Ref. ); (B) Hospitalized subjects given GR-rich BSE (mean 18.0%, data from Ref. ); (C) Free-living subjects given GR-rich BSE (mean 11.8%, data from Ref. ); (D) Cohort 1 (BSE in water; mean 9.4%); (E) Cohort 3 (Xymogen BSdE in gel-caps; mean 10.4%); (F) Cohort <t>2</t> <t>(JHU</t> BSE in gel-caps; mean 10.3%); (G) Cohort 6 (FDBS in dilute pineapple-lime juice; mean 44%); (H) Cohort 5 (FDBS in acid-resistant gel-caps; mean 32.7%); ( I) Cohort 5 (FDBS in regular gel-caps; mean 35.1%); (J) Cohort 4 (BSdP; 35.9%). There is a highly significant difference between the means of D through F a (10.3%), and G through J b (39.6%), (p = 0.0000, by oneway anova).
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    Average 90 stars, based on 1 article reviews
    broccoli sprout extract (bse) - by Bioz Stars, 2026-02
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    Mean bioavailability of sulforaphane from broccoli sprout and seed preparations rich in glucoraphanin, as affected by matrix, mode, of delivery, and activity of myrosinase on its substrate.

    Journal: PLoS ONE

    Article Title: Sulforaphane Bioavailability from Glucoraphanin-Rich Broccoli: Control by Active Endogenous Myrosinase

    doi: 10.1371/journal.pone.0140963

    Figure Lengend Snippet: Mean bioavailability of sulforaphane from broccoli sprout and seed preparations rich in glucoraphanin, as affected by matrix, mode, of delivery, and activity of myrosinase on its substrate.

    Article Snippet: Broccoli sprout extracts (BSE) were prepared by Johns Hopkins University investigators as described previously [ , , , ].

    Techniques: Activity Assay

    Preparations are: Commercial broccoli seed extract (BSdE) formulated into gel-caps at 69 and 230 μmol/dose (10.4% conversion overall; , Cohort 3), and JHU BSE formulated (by Xymogen) into molar equivalent doses (10.3% conversion overall; , Cohort 2). There is no difference among the treatment groups overall (p = 0.0651 by repeated measures anova)

    Journal: PLoS ONE

    Article Title: Sulforaphane Bioavailability from Glucoraphanin-Rich Broccoli: Control by Active Endogenous Myrosinase

    doi: 10.1371/journal.pone.0140963

    Figure Lengend Snippet: Preparations are: Commercial broccoli seed extract (BSdE) formulated into gel-caps at 69 and 230 μmol/dose (10.4% conversion overall; , Cohort 3), and JHU BSE formulated (by Xymogen) into molar equivalent doses (10.3% conversion overall; , Cohort 2). There is no difference among the treatment groups overall (p = 0.0651 by repeated measures anova)

    Article Snippet: Broccoli sprout extracts (BSE) were prepared by Johns Hopkins University investigators as described previously [ , , , ].

    Techniques:

    Preparations are: SF-, GR-, or GR plus Myrosinase-rich; they are delivered either in water, juice, or gel-caps; and they are derived from either sprouts or seeds, as indicated at top of graph. Boxes around data points delineate the 25 th to 75 th percentile of values, and whiskers delineate the 5 th and 95 th percentiles. Solid line through middle of box is the mean. “Cohort numbers” in the following are from : (A) Hospitalized subjects given SF-rich BSE (mean 68.9%, data from Ref. ); (B) Hospitalized subjects given GR-rich BSE (mean 18.0%, data from Ref. ); (C) Free-living subjects given GR-rich BSE (mean 11.8%, data from Ref. ); (D) Cohort 1 (BSE in water; mean 9.4%); (E) Cohort 3 (Xymogen BSdE in gel-caps; mean 10.4%); (F) Cohort 2 (JHU BSE in gel-caps; mean 10.3%); (G) Cohort 6 (FDBS in dilute pineapple-lime juice; mean 44%); (H) Cohort 5 (FDBS in acid-resistant gel-caps; mean 32.7%); ( I) Cohort 5 (FDBS in regular gel-caps; mean 35.1%); (J) Cohort 4 (BSdP; 35.9%). There is a highly significant difference between the means of D through F a (10.3%), and G through J b (39.6%), (p = 0.0000, by oneway anova).

    Journal: PLoS ONE

    Article Title: Sulforaphane Bioavailability from Glucoraphanin-Rich Broccoli: Control by Active Endogenous Myrosinase

    doi: 10.1371/journal.pone.0140963

    Figure Lengend Snippet: Preparations are: SF-, GR-, or GR plus Myrosinase-rich; they are delivered either in water, juice, or gel-caps; and they are derived from either sprouts or seeds, as indicated at top of graph. Boxes around data points delineate the 25 th to 75 th percentile of values, and whiskers delineate the 5 th and 95 th percentiles. Solid line through middle of box is the mean. “Cohort numbers” in the following are from : (A) Hospitalized subjects given SF-rich BSE (mean 68.9%, data from Ref. ); (B) Hospitalized subjects given GR-rich BSE (mean 18.0%, data from Ref. ); (C) Free-living subjects given GR-rich BSE (mean 11.8%, data from Ref. ); (D) Cohort 1 (BSE in water; mean 9.4%); (E) Cohort 3 (Xymogen BSdE in gel-caps; mean 10.4%); (F) Cohort 2 (JHU BSE in gel-caps; mean 10.3%); (G) Cohort 6 (FDBS in dilute pineapple-lime juice; mean 44%); (H) Cohort 5 (FDBS in acid-resistant gel-caps; mean 32.7%); ( I) Cohort 5 (FDBS in regular gel-caps; mean 35.1%); (J) Cohort 4 (BSdP; 35.9%). There is a highly significant difference between the means of D through F a (10.3%), and G through J b (39.6%), (p = 0.0000, by oneway anova).

    Article Snippet: Two types of highly standardized, lyophilized boiling water extracts of 3-day-old broccoli sprouts (BSE) have been prepared at Johns Hopkins University Medical School (JHU), utilizing good manufacturing (GMP) conditions, and have been used widely under clinical protocols approved by IRBs and under INDs approved by the FDA.

    Techniques: Derivative Assay

    Mean bioavailability of sulforaphane from broccoli sprout and seed preparations rich in glucoraphanin, as affected by matrix, mode, of delivery, and activity of myrosinase on its substrate.

    Journal: PLoS ONE

    Article Title: Sulforaphane Bioavailability from Glucoraphanin-Rich Broccoli: Control by Active Endogenous Myrosinase

    doi: 10.1371/journal.pone.0140963

    Figure Lengend Snippet: Mean bioavailability of sulforaphane from broccoli sprout and seed preparations rich in glucoraphanin, as affected by matrix, mode, of delivery, and activity of myrosinase on its substrate.

    Article Snippet: Two types of highly standardized, lyophilized boiling water extracts of 3-day-old broccoli sprouts (BSE) have been prepared at Johns Hopkins University Medical School (JHU), utilizing good manufacturing (GMP) conditions, and have been used widely under clinical protocols approved by IRBs and under INDs approved by the FDA.

    Techniques: Activity Assay

    Preparations are: Commercial broccoli seed extract (BSdE) formulated into gel-caps at 69 and 230 μmol/dose (10.4% conversion overall; , Cohort 3), and JHU BSE formulated (by Xymogen) into molar equivalent doses (10.3% conversion overall; , Cohort 2). There is no difference among the treatment groups overall (p = 0.0651 by repeated measures anova)

    Journal: PLoS ONE

    Article Title: Sulforaphane Bioavailability from Glucoraphanin-Rich Broccoli: Control by Active Endogenous Myrosinase

    doi: 10.1371/journal.pone.0140963

    Figure Lengend Snippet: Preparations are: Commercial broccoli seed extract (BSdE) formulated into gel-caps at 69 and 230 μmol/dose (10.4% conversion overall; , Cohort 3), and JHU BSE formulated (by Xymogen) into molar equivalent doses (10.3% conversion overall; , Cohort 2). There is no difference among the treatment groups overall (p = 0.0651 by repeated measures anova)

    Article Snippet: Two types of highly standardized, lyophilized boiling water extracts of 3-day-old broccoli sprouts (BSE) have been prepared at Johns Hopkins University Medical School (JHU), utilizing good manufacturing (GMP) conditions, and have been used widely under clinical protocols approved by IRBs and under INDs approved by the FDA.

    Techniques: